Selective alkylation of T–T mismatched DNA using vinyldiaminotriazine–acridine conjugate
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چکیده
منابع مشابه
Selective alkylation of T–T mismatched DNA using vinyldiaminotriazine–acridine conjugate
The alkylation of the specific higher-order nucleic acid structures is of great significance in order to control its function and gene expression. In this report, we have described the T-T mismatch selective alkylation with a vinyldiaminotriazine (VDAT)-acridine conjugate. The alkylation selectively proceeded at the N3 position of thymidine on the T-T mismatch. Interestingly, the alkylated thym...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2018
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gkx1278